Novogene - 2021_NovThanksgivingDay

As Thanksgiving 2021 draws near, we believe there must be good things happening in your life that make you feel grateful and wish to celebrate just like us.

With a decade of dedication and innovation, Novogene has fostered collaboration with our valued customers like you and has attained rapid development in the field of genetic technology by offering leading-edge NGS services and solutions. From library preparation and sequencing to bioinformatics analysis, we seek to bring you deeper insights into life sciences with the industry-leading data quality and the fastest turnaround time.

In this festive season, we sincerely appreciate your continued support and the trust you’ve placed in us. You made us who we are today, and let’s celebrate Thanksgiving together! Meanwhile, we have a Special Gift for you. Get yours now before the offer ends!

How to Participate? Easy!

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Applicable if Quotation Amount ≥ $3000 and issued between November 4t^h to 30^th, with PO or samples arrive before December 15^th, 2021
Not applicable with any other promotions

Novogene Corporation Inc.

8801 Folsom Blvd #290, Sacramento, CA 95826

916-252-0068-383 inquiry_us@novogene.com en.novogene.com

Novogene’s mRNA-Seq offers comprehensive solutions for analysis of gene expression quantification and differential gene expression among sample groups, as well as for identification of novel transcripts, alternative splicing, gene fusion events, etc. Our experienced bioinformaticians work closely with customers to provide standard and customized data analysis and publication-ready results for species with or without a reference genome. Besides of the eukaryotic mRNA sequencing above, we also offer prokaryotic RNA sequencing service, please contact us for more details.

lncRNA Sequencing

Long non-coding RNA sequencing service (lncRNA-seq) is a comprehensive next-generation method to detect the transcripts with a length of over 200nt, which do not encode protein and perform as regulatory elements in multiple biological processes. Effects of lncRNAs show evidence on multiple cellular functions and perform as prime targets on the regulation of gene transcription, post-transcriptional modifications, and epigenetics.

Small RNA Sequencing

Novogene sRNA-seq service is an effective approach to selectively target any species of sRNAs with unprecedented sensitivity and high resolution, all in a single analysis. Coupled with a robust in-house bioinformatics pipeline, Novogene sRNA-seq service has been assisting researchers to describe the differential expression of miRNAs, structural alterations, and to discover novel sRNAs.

circRNA Sequencing

Circular RNA (circRNA) molecules are a novel type of non-coding transcripts that are equipped with covalently closed loop lacking 5’ end caps and 3’ poly(A) tails. The stable structure enables the circular transcripts resistant to the exonuclease digestion and provides mechanism for library construction with linear transcripts digested by RNase R. Novogene circRNA sequencing service (circRNA-seq) supports investigation on miRNA sponges and fulfills the regulatory function in gene expression.

Whole Transcriptome Sequencing

Novogene’s Whole Transcriptome Sequencing service equips the researcher with cutting-edge NGS solutions that provide in-depth bioinformatic analysis on all transcripts including mRNAs and non-coding RNAs. This competitive approach investigates and explores potential transcriptional and regulatory network mechanisms, while providing key insights into interaction and intersection functionality from a comprehensive transcriptomic perspective.

Full-length Transcript Sequencing (Iso-Seq)

Isoform Sequencing Service (Iso-Seq), based on cutting-edge PacBio SMRT (Single Molecule, Real Time) technology, enables full-length reads being sequenced of entire transcript isoforms from 5’ UTR to 3’ polyadenylation without assembly required. Iso-seq is an ultra high-throughput method for characterizing gene fusion, alternative splicing and gene fusion events and improving annotations for genomes and discovery of novel transcripts by complementing for the potential error by the short reads.

Metatranscriptome Sequencing

Metatranscriptome refers to the total content of gene transcripts (RNA copies of the genes) in a nature community (i.e., soil, water, sea, feces, and gut), considered as a unique entity, at a specific moment of sampling. Through identifies gene expression in both eukaryotes and prokaryotes, this service allows you to obtain whole gene expression profiling of complex microbial communities, taxonomic analysis of species, functional enrichment analysis of differently expressed genes, and more.

Shotgun Metagenomic Sequencing

Shotgun metagenomic sequencing provides information on the total genomic DNA from all organisms in a sample, avoiding the need for isolation and cultivation of microorganisms or amplification of target regions. Novogene uses next-generation sequencing (NGS) technology to provide not only information on the taxonomic annotations of each organism but also the functional profiling, gene prediction and microbial interaction of the whole community.

Whole Exome Sequencing (Human/Mouse)

Whole exome sequencing (WES) employs next-generation sequencing technology (NGS), which provides a cost-efficient alternative to whole genome sequencing (WGS). Through targeting exons (protein-coding region of the genome), WES provides an in-depth sequencing and analysis approach to indicate germline mutations, somatic mutations, and pathogenic mechanisms.

Whole Exome Sequencing (Human/Mouse)

Whole exome sequencing (WES) employs next-generation sequencing technology (NGS), which provides a cost-efficient alternative to whole genome sequencing (WGS). The human whole exome, composed by about 180,000 exons (protein-coding region of the genome) accounts for only 1-2% of the human genome, but up to 85% of the disease-related mutations associated with Mendelian disorders occur in these regions [1]. By targeting these regions, human whole exome sequencing (hWES) provides an in-depth sequencing and analysis approach to indicate genome variants, germline mutations, somatic mutations, and pathogenic mechanisms. hWES service supports a broad range of studies for researchers, including genetic disease-related variants, complex diseases, cancer research, or human population genetics.

Target Region Sequencing

Targeted Region Sequencing focuses on a subset of genes or specific regions of the genome, which are most likely to be involved in the phenotype under study. Targeted sequencing is a cost-effective method for investigating areas of interest, and can also deliver much higher coverage levels, allowing identification of rare variants.

De novo Sequencing

De novo sequencing generates an initial genomic sequence of a particular organism without a reference genome. Services can be applied to research of animals, plants, and microorganisms, including phylogenetic studies, analysis of species diversity, genetic markers, and other genomic research.

Whole Genome Sequencing on NovaSeq/PacBio/Nanopore (Human/Animal/Plant/Microbe)

Whole Genome Sequencing (WGS) provides a deep insight into the DNA sequence of humans, animals, plants, and microbial genomes, with data analysis at the individual or population level. SNP/INDEL/CNV/SV and other variants of the genome can be fully analysed.

Watch a webinar to learn more

Pre-made Library Sequencing

With the world-leading, powerful, and sophisticated Illumina sequencing platforms, Novogene provide sequencing services for the pre-made libraries at different read lengths and capacities to suit any cost, project scale, and turnaround.

RNA Immunoprecipitation Sequencing (RIP-Seq)

RNA immunoprecipitation sequencing (RIP-seq) is a high-throughput RNA sequencing method widely used to study Protein-RNA interactions to detect RNA interactions with the target proteins. RIP-seq provides deep insights not only into the central dogma (i.e., transcription and translation) but also in recent research areas like gene regulation by ncRNAs and RNA interference.

Reduced Representation Bisulfite Sequencing (RRBS)

Reduced Representation Bisulfite Sequencing (RRBS) is an accurate, efficient, and economical method for DNA methylation research. Enrichment of promoter and CpG island regions by enzymatic cleavage (Msp I), combined with Bisulfite sequencing, provides high resolution DNA methylation detection.

Whole Genome Bisulfite Sequencing (WGBS)

Novogene provides whole genome bisulfite sequencing (WGBS) to efficiently identify methylated cytosines on a genome-wide scale with a single nucleotide resolution. The deep reach of the methylome is imperative for understanding gene expression and multiple biological processes that are subject to epigenetic regulation.

Chromatin Immunoprecipitation Sequencing (ChIP-Seq)

Chromatin immunoprecipitation sequencing (ChIP-Seq) provides genome-wide profiling of DNA targets for histone modification, transcription factors, and other DNA-associated proteins. It combines the selectivity of ChIP to recover specific protein-DNA complexes, with the power of next-generation sequencing (NGS) for high-throughput sequencing of the recovered DNA.

Amplicon Metagenomic Sequencing (16S/18S/ITS)

Novogene amplicon metagenomic sequencing services provide efficient detection of microbial composition in target organisms, as well as to describe and compare the diversity of multiple complex environments. The approach is frequently used in population and community microbial ecology studies, phylogenetic reconstruction of target microbial groups, identification of individual species in pure cultures, and detection of organisms of interest (pathogens or beneficial), among many others.